Flavonoids: What is it and how does it work?

Flavonoids image

In the world of hemp and hemp-derived CBD and THC products, there’s a growing interest in the compounds that contribute to the plant’s therapeutic properties.

Among these compounds, flavonoids stand out as intriguing and potentially beneficial elements.

In this article, we will delve into the realm of hemp flavonoids, understanding what they are and exploring how they work to enhance the therapeutic potential of hemp and hemp-derived products.

What are flavonoids?

Flavonoids are a diverse group of natural compounds found abundantly in the cannabis sativa plant, like cannabis and hemp. Produced mainly in tiny trichomes on flowers and leaves, these compounds also contribute to the plant’s therapeutic properties.

Flavonoids are part of a larger group of plant compounds, and they contribute to the plant’s color, flavor, and overall health. In hemp, flavonoids are diverse and include various types such as flavones, flavonols, flavanones, and anthocyanins.

The flavonoids are synthesized through complex biochemical processes in the plant, and each type has distinctive properties that contribute to the overall health potential of hemp-derived products.

Types of flavonoids

Types of flavonoids in full spectrum CBD image

The major types of flavonoids found in hemp include:

  1. Quercetin is a flavonoid renowned for its potent antioxidant and anti-inflammatory properties. It helps combat oxidative stress and inflammation in the body.
  2. Apigenin exhibits a range of health-promoting qualities, including antioxidant, anti-inflammatory, and potential neuroprotective effects. It is recognized for its positive impact on cellular health.
  3. Kaempferol is a flavonoid known for its antioxidant and anti-inflammatory properties. It contributes to cellular health and plays a role in protecting the body from various stressors.
  4. Luteolin is recognized for its antioxidant and anti-inflammatory effects, contributing to overall well-being. It is associated with immune system support and cellular health.
  5. Cannflavin A, B, and C are exclusive to cannabis and hemp plants, cannflavins have gained attention for their potential anti-inflammatory effects. While research is ongoing, initial findings suggest promise in managing inflammation.

Other lesser-known hemp flavonoids include flavones, flavonols, flavanones, and isoflavones.

How do flavonoids work?

Hemp flavonoids work by interaction with the body’s endocannabinoid system (ECS) and other molecular pathways. Here’s a simplified explanation:

Interaction with the endocannabinoid system (ECS): Flavonoids in hemp can interact with the ECS, which is a complex cell-signaling system in the body that is involved in regulating various physiological processes such as mood, appetite, and inflammation.

Enhancing the entourage effect: The entourage effect refers to the synergistic interaction of various compounds in the hemp plant, including cannabinoids, terpenes, and flavonoids. Hemp flavonoids work in harmony with other plant compounds to enhance the overall therapeutic effects of hemp and hemp-derived CBD and THC products (1).

Antioxidant power: One of the primary roles of hemp flavonoids is their antioxidant activity. Antioxidants combat oxidative stress by neutralizing free radicals in the body. Free radicals, which result from factors like pollution, UV radiation, and inflammation, can damage cells and contribute to various health issues (2).

Hemp flavonoids, with their antioxidant prowess, help protect the body’s cells from this oxidative damage, supporting overall well-being.

Anti-inflammatory properties: Hemp flavonoids have demonstrated anti-inflammatory effects, which can potentially mitigate inflammatory processes in the body. This makes them a promising candidate for those seeking natural alternatives to manage inflammatory conditions.

Neuroprotective effects: Some hemp flavonoids have also shown neuroprotective properties, indicating potential benefits for brain health. Research suggests that these compounds can help protect nerve cells from damage, potentially playing a role in the prevention or management of neurodegenerative diseases (3).

Are flavonoids safe?

Hemp flavonoids are usually safe for most people, and many use flavonoid-infused products without any problems. But, there are a few things to keep in mind:

First, everyone’s body is different. What works well for one person might not be the same for another. So, it’s essential to pay attention to how your body reacts.

The safety of hemp-derived products also depends on their quality. It’s important to choose products from trusted sources that follow quality standards. This helps minimize any potential risks.

Additionally, make sure the hemp-derived products you use follow local regulations. They should also have legal levels of delta-9 THC (less than 0.3%).

Always follow the recommended doses and usage instructions provided by the product’s maker. Keeping things moderate and making informed choices will help you have a safe and positive experience with hemp flavonoids.

Furthermore, before trying hemp products with flavonoids, especially if you have health issues or take medications, it’s a good idea to talk to your doctor. They can give you advice based on your specific situation.

Final thoughts

To sum up, hemp flavonoids show a lot of promise for our well-being. They’re found in hemp-derived THC, full-spectrum CBD, and broad-spectrum CBD products and can be used in different ways, like as supplements and skincare products. These flavonoids have beneficial qualities like reducing inflammation and helping our bodies fight off harmful stuff.

Flavonoids are also good for our skin, brain, and heart health.

Using products with hemp flavonoids could be a smart choice, but it’s essential to follow the instructions and talk to a doctor if needed.


The information in this article is intended for general use only and may not always be appropriate for everyone’s needs. Your health and wellness are unique to you, so before acting on anything we say, seek personalized advice from a medical professional.

We value the accuracy and editorial integrity of all our articles, and we strive to ensure that the content we publish is accurate and up-to-date to the best of our knowledge.