Can CBD Affect THC Tolerance? What You Need to Know

Does cbd affect THC tolerance

If you are a THC user and planning to take CBD and wondering if taking CBD will be useful or not, or whether CBD and THC together are going to affect the tolerance of cannabis in your system, then this article is for you.

Cannabinoids like “CBD” and “THC” have a unique way of interacting with your body. Both have different effects, but somehow CBD seems to alter the tolerance of THC in your body.

CBD is a “non-psychoactive compound” and THC is a “psychoactive compound” that can be found in both cannabis and hemp plants. Both cannabinoids have unique properties and effects, so how come CBD can alter THC tolerance while it’s not the other way around?

To understand this clearly, we have to understand how THC and CBD work in your body. 

THC effects and tolerance explained

THC, short for “tetrahydrocannabinol”, is a psychoactive compound of the cannabis and hemp plants. 

The THC works by binding to the CB receptors, mostly the CB1 receptor that is concentrated in the brain and the CB2 receptor that is scattered in the body, which leads to altering of your senses and gives you a euphoric sensation, also known as “high”.

While consuming cannabis sativa, the THC is mainly going to bind with the CB1 receptor, giving you the feeling of a head high. Similarly, when consuming Cannabis indica, the THC is going to bind with both CB1 and CB2 receptors giving you the feeling of a body high.

If you use THC regularly for some time, you are going to develop a tolerance toward it, meaning you are going to feel the diminishing effects or be less high at a similar dosage.

With constant use, the dosage of THC needed for you to get the previous sensation or to get “stoned” is going to increase and you are going to develop a tolerance toward THC.

To deal with the tolerance, you can take a tolerance break to give the body’s receptors a chance to wind down and recover. The exact time for a tolerance break depends on the person, the duration of use, and the amount of THC products used.  But it’s safe to say that a tolerance break of 10 to 15 days from THC is going to be enough for most regular users to reset their system.

However, you can also take CBD to manage THC tolerance. 

CBD effects and tolerance explained

CBD, short for “cannabidiol”, is a non-psychoactive compound of cannabis and hemp plants that has many therapeutic benefits.

The CBD works by interacting with your body’s endocannabinoid system and CB receptors similar to THC, but it indirectly regulates the receptors that are scattered in the body and mind to help them reach a state of homeostasis. 

However, CBD does not cause any sense-altering effects, rather, it exhibits therapeutic properties like anti-anxiety, anti-inflammation, pain relief, and insomnia relief.

That’s the reason CBD is in the craze right now, it will likely be more popular in the near future.

Moreover, unlike THC, you can not develop a tolerance to CBD, rather if you are using CBD every day at a certain dosage for certain benefits, after some time you will notice that the required dosage to reach that benefit will decrease.

This happens because once your body’s endocannabinoid system and receptors adjust to the CBD and reach a certain stage of homeostasis, they do not require more dosage. Instead, they are going to need a lot less dose of CBD for the same results.

So the long-term use of CBD actually results in building a reverse tolerance.

If both CBD and THC are taken together or at a difference of a few hours, their effects will overlap, meaning CBD is going to interact with THC in your body. 

How does CBD affect THC?

If you take both CBD and THC together, the CBD is going to alter the effects of THC, since both cannabinoids interact with the bunch of same receptors, you are going to feel less of a buzz when you were taking just THC.

CBD also helps manage and reduce the unwanted psychoactive effects of THC, such as extreme euphoria, panic, anxiety, or sedation.

CBD generally tames the feeling of “high” caused by THC.

However, you are still going to feel the effects of THC, but it will be more tolerable and a lot less milder with CBD.

Both CBD and THC work by interacting with your body’s receptors but CBD does not interact in a similar manner as THC does. As a higher dosage of THC hyperaroused your body’s cannabinoid receptors and overwhelms the endocannabinoid system and the more THC you take the more active it becomes. 

So there is a constant need of taking more THC to get a similar “high”.

While CBD helps the receptors reach a more balanced state, and once that balanced state is reached, then increasing the dose of CBD will just be ineffective and useless.

CBD also helps curb the side effects of THC. 

How does CBD manage THC tolerance?

Once you develop a tolerance to THC, you will require an even higher dosage to reach the desired effects and this will require you to increase the dosage, which generally comes with many discomforts like the feeling of panic, anxiety, poor motor skills, and a decrease in response time.

Many people deal with this by taking a tolerance break from THC. which can last somewhere between 3 to 15 days or more depending on the person and usage. However, there is one more effective solution for it, take CBD.

Although there are not many studies available, one study has reported that CBD can lower THC tolerance and it can also deal with the intoxicating feeling in a faster and better way.

What CBD does is, it balances some of the cannabinoid receptors that were hyper-aroused by THC and helps them regain their natural self. 

Some people who have taken CBD during the tolerance break from THC, have also reported having faster recovery time and better results from the tolerance break.

However, it’s not the case for everyone. CBD works differently for everybody, so for some, it’s possible that CBD might just not work as effectively to deal with THC tolerance. 

Final thoughts

CBD and THC both are the two faces of a coin, they work similarly but they are quite different from each other. As far as the tolerance goes, CBD doesn’t cause any. However, THC does.

To deal with the THC tolerance, you can take a tolerance break or you can take CBD in the mix. CBD might help you deal with the THC tolerance in a faster and more effective way.

Nevertheless, CBD and THC work differently for everyone, so keeping an open mind in figuring out what works for you is the way to go. 


The information in this article is intended for general use only and may not always be appropriate for everyone’s needs. Your health and wellness are unique to you, so before acting on anything we say, seek personalized advice from a medical professional.

We value the accuracy and editorial integrity of all our articles, and we strive to ensure that the content we publish is accurate and up-to-date to the best of our knowledge.